Mechanistic explanations of cell-level phenomena rarely study behavior from a cell's perspective. Agent-based models lend themselves to model from an individual's perspective, and we extend that with a framework which utilizes a cell's perspective in an off-lattice environment. We aim to help increase the understanding of biological phenomena through our Delaunay and Voronoi off-lattice agent-based, discrete event framework. We focus on biological cells and expand on existing cell- and agent-centered methods by offering a new perspective in an off-lattice environment.